双语新闻 :懒人福音:“运动药丸”有望取代健身房
[p=26, 2, left][size=4]想健身却懒得动?今后一粒药丸就能帮你!科学家表示,他们有望研制出一种能帮你长肌肉,同时远离肥胖的药物。这种药物还能帮助人们治疗肌肉萎缩疾病,以及心血管功能异常。[/size][/p][size=4][attach]21126[/attach]
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[/size][/p][p=26, 2, left][size=4]An “exercise pill” that could reduce the need for visits to the gym is a step closer, say scientists.[font=Arial, Helvetica, sans-serif][color=#000000] [/color][/font]
[font=Arial, Helvetica, sans-serif][color=#000000]科学家称,他们离制造出“运动药丸”从而减少人们前往健身房次数的目标更进一步。[/color][/font][/size][/p][p=26, 2, left][size=4]A study found that suppressing production of the protein myostatin increased muscle mass.
一项研究发现,阻止肌肉生长抑制蛋白的生成可以提升肌肉质量。[/size][/p][p=26, 2, left][size=4]Although the research was conducted in mice, the team hopes it will lead to human treatments.
尽管这一实验还停留在试验小白鼠的阶段,科研团队希望后续能够用于人类治疗。[/size][/p][p=26, 2, left][size=4]Lead researcher Dr Joshua Butcher, from Augusta University in Georgia, US, said: "Ultimately, the goal of our research would be to create a pill that mimics the effect of exercise and protects against obesity.
来自美国乔治尼亚州奥古斯塔大学的首席研究员约书亚•布彻博士说:“我们实验的最终目的是创造出一种药物,拥有和运动一样的功效并且可以预防肥胖症。”[/size][/p][p=26, 2, left][size=4]"A pill that inhibits myostatin could also have applications for muscle-wasting diseases, such as cancer, muscle dystrophy and AIDS, Myostatin is known to be a powerful "brake" that holds back skeletal muscle growth."
“阻止肌肉抑制素生成的药物同时也可以用于治疗肌肉萎缩类疾病,比如癌症、肌肉萎缩病还有艾滋病。肌肉抑制素广为人知的作用就是有效抑制骨骼肌的生长。”[/size][/p][p=26, 2, left][size=4]Studies suggest that obese people produce more of the protein, making it harder for them to exercise and build up muscle.
研究表明,肥胖的人会产生更多肌肉生长抑制素这种蛋白质,这让他们更难进行运动和增肌。[/size][/p][p=26, 2, left][size=4]"Given that exercise is one of the most effective interventions for obesity, this creates a cycle by which a person becomes trapped in obesity," said Dr Butcher.
布彻博士说:“而运动又是防止肥胖的最有效方式之一,这就导致肥胖的人陷入恶性循环。”[/size][/p][p=26, 2, left][size=4]The researchers bred four groups of lean and obese mice that were genetically programmed either to produce uninhibited levels of myostatin or to be completely lacking in the protein.
研究人员饲养了四组瘦弱和肥胖的小白鼠,其基因设定分别为无限制释放肌肉抑制素和完全不释放肌肉抑制素。[/size][/p][p=26, 2, left][size=4]As expected, mice with no myostatin became markedly more muscular.
同预期一样,体内不释放肌肉抑制素的小白鼠明显肌肉更强壮。[/size][/p][p=26, 2, left][size=4]Obese mice unable to produce myostatin remained fat, but they were also stronger and showed markers of heart and metabolic health on a par with their lean counterparts.
那些不能释放肌肉抑制素的肥胖小白鼠依然保持肥胖,但同时也变得更加强壮。与瘦弱的对照小白鼠相比,它们的心脏和新陈代谢表现的更加健康。[/size][/p][p=26, 2, left][size=4]They were in dramatically better shape than obese mice with unrestricted myostatin production.
与那些无限释放肌肉抑制素的小白鼠相比,这些小白鼠的体型要健康得多,这令人惊讶。[/size][/p][p=26, 2, left][size=4]Dr Butcher added: "In our muscular obese mouse, despite full presentation of obesity, it appears that several of these key pathologies are prevented.
布彻博士补充道:“这些肌肉发达却肥胖的小白鼠,尽管依然表现出肥胖的症状,但一些关键的病理症状没有发生。”[/size][/p][p=26, 2, left][size=4]"While much more research is needed, at this point myostatin appears to be a very promising pathway for protection against obesity-derived cardiometabolic dysfunction."
“虽然还需进行大量研究,但目前看来,肌肉抑制素似乎对于治疗由肥胖导致的心血管功能异常很有帮助。”[/size][/p][p=26, 2, left][size=4]The research was presented at the American Physiological Society's annual meeting, Experimental Biology 2017, in Chicago, US.
该研究在美国芝加哥举办的美国生理学协会2017年实验生物学年会上作了报告。[/size][/p][p=26, 2, left][size=4]英文来源:镜报[/size]
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